A genetic polymorphism and its genetic effects on goat myogenin gene in intron 1

Single nucleotide polymorphisms (SNPs) of the myogenin (MyoG) gene were tested using primer induced restriction fragment length polymorphism assay-polymerase chain reaction (PIRA-PCR) from Bore goat and its upgrading offspring to Tangshan diary goat (including F1, F2 and F3). The effects of the myogenin gene on the birth weight, 1-month body weight and the weaning weight were also analyzed. On the basis of the DNA sequence of the goat myogenin gene (FJ607135), primers were designed to amplify myogenin gene. The result showed that one polymorphism (transition of g.558C>T) was found in intron 1 of goat myogenin gene, in which two alleles (A and B) and three genotypes (AA, AB and BB) were examined. The distributions of three genotypes were basically identical in four goat populations, and allele A was the dominant gene. The effect of the myogenin genotypes on the birth weight, 1-month body weight and the weaning weight were all not significant (P > 0.05) due to the small number of BB gaots; however, the values of AA genotype goats and AB genotype goats were obviously higher than those of BB genotype goats for three growth traits, in the order of AA > AB > BB. These results suggest that the myogenin genotype has some effects on partial growth traits of goat, and selecting the individuals with A allele could be favorable to the birth weight, 1-month body weight and the weaning weight.Key words: goats, myogenin gene, primer induced restriction fragment length polymorphism assay-polymerase chain reaction (PIRA-PCR), genetic polymorphisms, genetic effects

Geometry of reduced density matrices for symmetry-protected topological phases

© 2016 American Physical Society. In this paper, we study the geometry of reduced density matrices for states with symmetry-protected topological (SPT) order. We observe ruled surface structures on the boundary of the convex set of low-dimensional projections of the reduced density matrices. In order to signal the SPT order using ruled surfaces, it is important that we add a symmetry-breaking term to the boundary of the system - no ruled surface emerges in systems without a boundary or when we add a symmetry-breaking term representing a thermodynamic quantity. Although the ruled surfaces only appear in the thermodynamic limit where the ground-state degeneracy is exact, we analyze the precision of our numerical algorithm and show that a finite-system calculation suffices to reveal the ruled surface structures

Excitonic quantum confinement modified optical conductivity of monolayer and few-layered MoS2

2016-2017 > Academic research: refereed > Publication in refereed journal201804_a bcmaVersion of RecordPublishe

Threshold-voltage instability of polymer thin-film transistor under gate-bias and drain-bias stresses

Polymer thin-film transistors (PTFTs) based on MEH-PPV semiconductor are fabricated by spin-coating process and characterized. Gate-bias and drain-bias stress effects at room temperature are observed in the devices. The saturation current decreases and the threshold voltage shifts toward negative direction upon the gate-bias stress. However, the saturation current increases and the threshold voltage shifts toward positive direction upon the drain-bias stress. For variable bias stress conditions, carrier mobility is almost unchanged. The results suggest that the origin of threshold-voltage shift upon negative gate-bias stress is predominantly associated with holes trapped within the SiO 2 gate dielectric or at the SiO 2/Si interface due to hotcarrier emission under high gate-bias stress, while time-dependent charge trapping into the deep trap states in the channel region is responsible for the drain-bias stress effect in the PTFTs. © 2008 IEEE.published_or_final_versio

The evaluation of the bone graft survival status in titanium cervical cages by radionuclide bone CT scan

To find a better way to evaluate the bone graft survival status in cervical cages, forty-one patients suffering from one-level cervical spondylosis were enrolled in this study. All underwent anterior cervical decompression and fusion with titanium cage and plate. When followed up, another 21 patients were confirmed as one-level cervical spondylosis without operation and were enrolled as control group. "Bolus" injection of radioactive 99mTc methylene diphosphonate (99mTc-MDP) with a dose of 25 ~ 30 mCi was performed through cubital vein, and radionuclide distribution images of cervical spine were obtained by single photon emission computed tomography/computed tomography (SPECT/CT). In sagittal view, bone graft was positioned accurately. By “region of interest” (ROI) technique, the same regions in bone graft and thoracic vertebra with the same level of suprasternal fossa were selected. Radioactive count ratio was then obtained. In the control group, “bone graft” was chosen on the inferior vertebra of the lesion segment, and the ratio was similarly gotten. Statistical difference was shown between bone graft group and control group by t test (t = 2.713, P < 0.05). The bone graft survival rate was 100% by SPECT/CT and bony fusion rate was 92.7% by CT scan. It indicated that in all bony fusion cases, bone graft survived; however, the bone survival was not surely together with bony fusion.Key words: Bone graft, titanium cervical cage, radionuclide bone CT

Interleukin-6 but not soluble adhesion molecules has short-term prognostic value on mortality in patients with acute ST-segment elevation myocardial infarction

Inflammatory responses represent an important element in all phases of the atherosclerotic process. This recognition has stimulated the evaluation of different inflammatory markers as potential predictors of cardiovascular risk. This study was designed to simultaneously measure serum levels of interleukin- 6 (IL-6), soluble intercellular adhesion molecule-1 (sICAM-1), soluble vascular cell adhesion molecule-1 (sVCAM-1), and soluble P-selectin (sP-selectin) in patients with acute ST-segment elevation myocardial infarction (STEMI) and to evaluate their ability to predict short-term prognosis. We recruited 263 consecutive patients admitted to our institute within 6 h of symptoms onset with the diagnosis of first STEMI. Clinical data were recorded and serum admission levels of IL-6, sICAM-1, sVCAM-1 and sPselectin were measured. The patients were then followed prospectively for the occurrence of cardiovascular mortality for 4 weeks. Nineteen (7.2%) patients died during the 4 weeks. The admission levels of IL-6 were significantly higher in patients who died from cardiovascular causes, whereas sICAM-1, sVCAM-1, and sP-selectin were not. Kaplan–Meier plots demonstrated a significant increase in cardiovascular mortality with increasing IL-6 levels (P = 0.0060). Logistic regression analysis revealed that IL-6 was an independent predictor for cardiovascular mortality. The present study indicates that elevated admission level of IL-6 but not soluble adhesion molecules could provide valuable information for short-term risk stratification in patients with STEMI.Key words: Acute ST-segment elevation myocardial infarction, interleukin-6, soluble intercellular adhesion molecule-1, soluble vascular cell adhesion molecule-1, soluble P-selectin, cardiovascular mortality

Physical origins of ruled surfaces on the reduced density matrices geometry

© 2016, Science China Press and Springer-Verlag Berlin Heidelberg. The reduced density matrices (RDMs) of many-body quantum states form a convex set. The boundary of low dimensional projections of this convex set may exhibit nontrivial geometry such as ruled surfaces. In this paper, we study the physical origins of these ruled surfaces for bosonic systems. The emergence of ruled surfaces was recently proposed as signatures of symmetry-breaking phase. We show that, apart from being signatures of symmetry-breaking, ruled surfaces can also be the consequence of gapless quantum systems by demonstrating an explicit example in terms of a two-mode Ising model. Our analysis was largely simplified by the quantum de Finetti’s theorem—in the limit of large system size, these RDMs are the convex set of all the symmetric separable states. To distinguish ruled surfaces originated from gapless systems from those caused by symmetry-breaking, we propose to use the finite size scaling method for the corresponding geometry. This method is then applied to the two-mode XY model, successfully identifying a ruled surface as the consequence of gapless systems